NFL

NFL odds, lines, point spreads: Updated Week 5 betting information for picking every game

Despite Patrick Mahomes’ late-game slide helping Jets’ spread bettors and sportsbooks finish the Sunday slate on a high note, the betting public — who tends to bet on the favorites — had a successful Week 4. Favorites went a profitable 9-5-1 ATS, and although Mahomes was a yard and a half away from potentially boosting the chalk’s Week 4 cover rate, the public can’t be too upset with how this past week unfolded. 

As we head into Week 5, the first set of byes sees the Chargers, Buccaneers, Seahawks, and Browns idle, resulting in a condensed 14-game slate. Week 5 kicks off on Thursday night with the 2-2 Commanders (-6.5) hosting the 0-4 Bears. Come Sunday, the Jaguars play their second straight game in London, doing battle against the AFC East-leading Bills (-5.5). Other notable matchups include the Rams (+4.5) and Eagles, and 49ers (-3.5) and Cowboys. Can favorites post another profitable week, or will underdogs even the score? 

Below, we’ll look at the latest odds for Week 5 from BetMGM and offer up a couple of early bets to consider. Keep in mind these lines will move throughout the week as we get updates on the playing status of key starters and betting limits increase. 

NFL odds Week 5

Odds courtesy of BetMGM. Click HERE to sign up!

Game Spread
Washington Commanders vs. Chicago Bears WAS -1.5 (-110)
Buffalo Bills vs. Jacksonville Jaguars BUF -3 (-110)
Atlanta Falcons vs. Houston Texans ATL -1.5 (-110)
Detroit Lions vs. Carolina Panthers DET -9 (-110)
Indianapolis Colts vs. Tennessee Titans IND -1.5 (-110)
Miami Dolphins vs. New York Giants MIA -9.5 (-110)
New England Patriots vs. New Orleans Saints NE -1.5 (-110)
Pittsburgh Steelers vs. Baltimore Ravens PIT +4.5 (-110)
Los Angeles Rams vs. Philadelphia Eagles LAR +4.5 (-110)
Arizona Cardinals vs. Cincinnati Bengals ARI +4 (-110)
Denver Broncos vs. New York Jets DEN -2.5 (-115)
Minnesota Vikings vs. Kansas City Chiefs MIN +5.5 (-110)
San Francisco 49ers vs. Dallas Cowboys SF -3.5 (-110)
Las Vegas Raiders vs. Green Bay Packers LV +1.5 (-110)

NFL moneylines Week 5

Game Moneyline
Washington Commanders vs. Chicago Bears WAS -275 | CHI +220
Buffalo Bills vs. Jacksonville Jaguars BUF -250 | JAX +200
Atlanta Falcons vs. Houston Texans ATL -120 | HOU +100
Detroit Lions vs. Carolina Panthers DET -450 | CAR +340
Indianapolis Colts vs. Tennessee Titans IND -120 | TEN +100
Miami Dolphins vs. New York Giants MIA -450 | NYG +350
New England Patriots vs. New Orleans Saints NE -125 | NO +105
Pittsburgh Steelers vs. Baltimore Ravens BAL -225 | PIT +180
Los Angeles Rams vs. Philadelphia Eagles PHI -210 | LAR +170
Arizona Cardinals vs. Cincinnati Bengals CIN -200 | ARI +165
Denver Broncos vs. New York Jets DEN -145 | NYJ +120
Minnesota Vikings vs. Kansas City Chiefs KC -225 | MIN +185
San Francisco 49ers vs. Dallas Cowboys SF -175 | DAL +145
Las Vegas Raiders vs. Green Bay Packers GB -125 | LV +105

NFL over/unders Week 5

Game Over/Under
Washington Commanders vs. Chicago Bears 44.5
Buffalo Bills vs. Jacksonville Jaguars 48
Atlanta Falcons vs. Houston Texans 41
Detroit Lions vs. Carolina Panthers 43.5
Indianapolis Colts vs. Tennessee Titans 41.5
Miami Dolphins vs. New York Giants 49.5
New England Patriots vs. New Orleans Saints 39
Pittsburgh Steelers vs. Baltimore Ravens 40
Los Angeles Rams vs. Philadelphia Eagles 48
Arizona Cardinals vs. Cincinnati Bengals 42.5
Denver Broncos vs. New York Jets 42.5
Minnesota Vikings vs. Kansas City Chiefs 52.5
San Francisco 49ers vs. Dallas Cowboys 45
Las Vegas Raiders vs. Green Bay Packers 44

NFL best bets for Week 5

*Odds and analysis as of Monday 10/2*

Jaguars +5.5 (-110) vs. Bills

Although the Bills enter Week 5 playing elite football over the past three weeks, boasting an uber-impressive +90 point differential, we’re taking the points and backing the “home” underdogs in this one. We think the market might be underestimating how beneficial it is that Jacksonville gets to stay in London to prep for his one. We’ve never seen a team play back-to-back games in London, so it’s tough to quantify that into the point spread, but a 5.5-point difference for a neutral site game between two well-rounded squads is too steep in our minds. 

Rams +4.5 (-110) vs. Eagles

While we are concerned about the Rams’ offensive line’s effectiveness against a stout Eagles defensive line, we think L.A. is a live dog in this one that can not only cover the spread but potentially win outright. Matthew Stafford is dealing with a hip injury suffered in the late stages of Sunday’s win over the Colts, but should be all systems go come Sunday. Despite being 4-0, the Eagles have shown some vulnerabilities in the early go. The Rams’ aerial attack could give the Eagles secondary some fits.

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